Dm8a [FBbt_00013774]
Dm8a
ID: FBbt_00013774
Glutamatergic (Gao et al., 2008; Karuppudurai et al., 2014) distal medullary amacrine neuron that branches extensively in medulla layer M6A (Fischbach and Dittrich, 1989; Takemura et al., 2013; Nern et al., 2015), spanning approximately 16 medulla columns (Karuppudurai et al., 2014), with centrifugal projections back to layer M4 (Takemura et al., 2013; Nern et al., 2015). The highest arbor density and longest distal projection are usually found in one optic column (its 'home column'), near the center of the M6A arborization, with these columns tiling between different individual Dm8 cells, while the rest of the arbor overlaps with other Dm8 cells considerably (Gao et al., 2008; Nern et al., 2015; Kind et al., 2021). In layer M6, it is postsynaptic to several R7 photoreceptor cells and presynaptic to Tm5c (Gao et al., 2008; Takemura et al., 2013; Karuppudurai et al., 2014). The contacts with Tm5c are clustered in one column at the center of the dendritic field of Dm8 (Karuppudurai et al., 2014). It is involved in UV preference (Gao et al., 2008).
Connectivity inferred from EM reconstructions from a single EM section. The neurotransmitter was assessed in cells labelled with a glutamate GAL4 driver P\{GawB}vGlut[OK371] (FBti0076967) (Gao et al., 2008), RT-PCR and by immunohistochemistry (Karuppudurai et al., 2014). Connectivity with R7 was assessed by EM reconstruction of a single medulla column (Gao et al., 2008) or reconstruction of serial-section TEM (Takemura et al., 2013).
Open in VFB 3D Browser →- Notch OFF hemilineage secondary neuron
- adult glutamatergic neuron
- distal medullary amacrine neuron
- optic lobe wide-field columnar neuron
- visual system neuron
Relationships
- capable_of_part_of: phototaxis, visual behavior
- develops from: immature distal medullary amacrine neuron Dm8a
- has synaptic IO in region: medulla layer M4
- receives synaptic input from neuron: photoreceptor cell R7
- receives synaptic input in region: medulla sublayer M6A
- sends synaptic output to cell: transmedullary neuron Tm5c
- sends synaptic output to region: medulla sublayer M6A
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| Dm8 | exact synonym | Hasegawa et al., 2011 |
| Dm8a | exact synonym | Schlegel et al., 2024 |
| Dm8a | exact synonym | Bates et al., 2025 |
| Dm8a | exact synonym | Berg et al., 2025 |
| Dm8a | exact synonym | |
| Dm8a | exact synonym | Nern et al., 2025 |
| Dm8 | exact synonym | Schlegel et al., 2024 |
| distal medullary amacrine neuron Dm8 | exact synonym | Hasegawa et al., 2011 |
List all available images of Dm8a (1315 total)
| Thumbnail | Name | Tags |
|---|---|---|
| Dm8a_L (MaleCNS:164150) | secondary_neuron, Nervous_system, Glutamatergic, Visual_system, Adult | |
| Dm8a_L (MaleCNS:77983) | secondary_neuron, Nervous_system, Glutamatergic, Visual_system, Adult | |
| Dm8a_L (MaleCNS:84634) | secondary_neuron, Nervous_system, Glutamatergic, Adult, Visual_system | |
| Dm8a_R (MaleCNS:83928) | secondary_neuron, Nervous_system, Glutamatergic, Adult, Visual_system | |
| Dm8a_R (MaleCNS:91156) | secondary_neuron, Nervous_system, Glutamatergic, Visual_system, Adult |
View all 1315 results in VFB →
Expression patterns overlapping Dm8a (5 total)
| Thumbnail | Name | Tags |
|---|---|---|
| P{R24F06-GAL4.DBD} ∩ P{R55F02-p65.AD} expression pattern | Split | |
| P{R15C01-GAL4.DBD} ∩ P{VT043162-p65.AD} expression pattern | Split | |
| P{GMR24F06-lexA} expression pattern | Expression_pattern | |
| P{GMR24F06-GAL4} expression pattern | Expression_pattern | |
| P{GawB}Dll[md23] expression pattern | Expression_pattern |
scRNAseq data for Dm8a (23 total)
| Thumbnail | Name | Tags |
|---|---|---|
| scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Dm8_neurons | Adult, Cluster, Nervous_system | |
| scRNAseq_2021_Ozel_ADM1_seq_clustering_Dm8_neurons | Adult, Cluster, Nervous_system | |
| scRNAseq_2022_FCA_MALE_FULL_seq_clustering_Dm8_amacrine_neurons | Adult, Cluster, Nervous_system | |
| scRNAseq_2022_FCA_FEMALE_FULL_seq_clustering_Dm8_amacrine_neurons | Adult, Cluster, Nervous_system | |
| scRNAseq_2022_FCA_FEMALE_HEAD_seq_clustering_Dm8_amacrine_neurons | Adult, Cluster, Nervous_system |
Transgene expression in Dm8a (4 total)
| Thumbnail | Name | Tags |
|---|---|---|
| P{R24F06-GAL4.DBD} ∩ P{R55F02-p65.AD} expression pattern | Split | |
| P{R15C01-GAL4.DBD} ∩ P{VT043162-p65.AD} expression pattern | Split | |
| P{GMR24F06-lexA} expression pattern | Expression_pattern | |
| P{GMR24F06-GAL4} expression pattern | Expression_pattern |
Downstream connectivity classes for Dm8a (185 total)
| Thumbnail | Name | Tags |
|---|---|---|
Upstream connectivity classes for Dm8a (156 total)
| Thumbnail | Name | Tags |
|---|---|---|
Feedback
Was this page helpful?
Glad to hear it! Please tell us how we can improve.
Sorry to hear that. Please tell us how we can improve.