DNp02 [FBbt_00047635]

Fruitless-expressing descending neuron belonging to the DNp group, having a large cell body posterior to the posterior lateral protocerebrum (Kimura et al., 2008; Matsuo et al., 2016; Namiki et al., 2018). In the brain, its postsynapses are found in the ipsilateral antennal mechanosensory and motor center zones A and B, wedge and the LC4 glomerulus of the posterior ventrolateral protocerebrum (Matsuo et al., 2016). It has presynapses in the gnathal ganglion and saddle (Matsuo et al., 2016). It does not cross the midline and descends on the ipsilateral side of the cervical connective (Namiki et al., 2018). In the VNC it follows the ventral medial tract of the ventral cervical fascicle and innervates the intermediate and lower tectulum, and the T2 leg neuropil (Namiki et al., 2018). It receives looming stimulus input from anterior LC4 neurons and its activity results in a backwards leaning posture and backwards takeoff (Dombrovski et al., 2023). There is one of these cells per hemisphere (Matsuo et al., 2016; Namiki et al., 2018) and it is cholinergic (Cheong et al., 2024).
DNp02 DNp02 DNp02 DNp02

DNp02

ID: FBbt_00047635

Adult Cholinergic Nervous system

Fruitless-expressing descending neuron belonging to the DNp group, having a large cell body posterior to the posterior lateral protocerebrum (Kimura et al., 2008; Matsuo et al., 2016; Namiki et al., 2018). In the brain, its postsynapses are found in the ipsilateral antennal mechanosensory and motor center zones A and B, wedge and the LC4 glomerulus of the posterior ventrolateral protocerebrum (Matsuo et al., 2016). It has presynapses in the gnathal ganglion and saddle (Matsuo et al., 2016). It does not cross the midline and descends on the ipsilateral side of the cervical connective (Namiki et al., 2018). In the VNC it follows the ventral medial tract of the ventral cervical fascicle and innervates the intermediate and lower tectulum, and the T2 leg neuropil (Namiki et al., 2018). It receives looming stimulus input from anterior LC4 neurons and its activity results in a backwards leaning posture and backwards takeoff (Dombrovski et al., 2023). There is one of these cells per hemisphere (Matsuo et al., 2016; Namiki et al., 2018) and it is cholinergic (Cheong et al., 2024).

Namiki et al. (2018), identify this as being morphologically similar to the lateral giant descending neuron, described by Milde and Strausfeld (1990) (FBrf0239829).

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
DNp02 exact synonym doi_10_7554_eLife_97766_1
DNlt003 exact synonym Stürner et al., 2025
DNp02 exact synonym Namiki et al., 2018
DNp02 exact synonym Bates et al., 2025
antennal mechanosensory and motor center AMMC P3b neuron exact synonym Stürner et al., 2025
DNp02 exact synonym Berg et al., 2025
DNp02 exact synonym
DNp02 exact synonym Scheffer et al., 2020
DNp02 exact synonym Schlegel et al., 2024
AMMC-P3b exact synonym Stürner et al., 2025

List all available images of DNp02 (13 total)

Thumbnail Name Tags
DNp02_L (MaleCNS:10197) Adult, Cholinergic, lineage_SMPpv2_CP1
DNp02_L (MaleCNS:10197) Adult, Cholinergic, lineage_SMPpv2_CP1
DNp02_R (MaleCNS:10117) Adult, Cholinergic, lineage_SMPpv2_CP1
DNp02_R (MaleCNS:10117) Adult, Cholinergic, lineage_SMPpv2_CP1
TBD (MANC:10331) Nervous_system, Adult, Cholinergic

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Expression patterns overlapping DNp02 (9 total)

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Transgene expression in DNp02 (9 total)

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Downstream connectivity classes for DNp02 (344 total)

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Upstream connectivity classes for DNp02 (240 total)

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