DNp02 [FBbt_00047635]
DNp02
ID: FBbt_00047635
Fruitless-expressing descending neuron belonging to the DNp group, having a large cell body posterior to the posterior lateral protocerebrum (Kimura et al., 2008; Matsuo et al., 2016; Namiki et al., 2018). In the brain, its postsynapses are found in the ipsilateral antennal mechanosensory and motor center zones A and B, wedge and the LC4 glomerulus of the posterior ventrolateral protocerebrum (Matsuo et al., 2016). It has presynapses in the gnathal ganglion and saddle (Matsuo et al., 2016). It does not cross the midline and descends on the ipsilateral side of the cervical connective (Namiki et al., 2018). In the VNC it follows the ventral medial tract of the ventral cervical fascicle and innervates the intermediate and lower tectulum, and the T2 leg neuropil (Namiki et al., 2018). It receives looming stimulus input from anterior LC4 neurons and its activity results in a backwards leaning posture and backwards takeoff (Dombrovski et al., 2023). There is one of these cells per hemisphere (Matsuo et al., 2016; Namiki et al., 2018) and it is cholinergic (Cheong et al., 2024).
Namiki et al. (2018), identify this as being morphologically similar to the lateral giant descending neuron, described by Milde and Strausfeld (1990) (FBrf0239829).
Open in VFB 3D Browser →- adult cholinergic neuron
- descending neuron of the posterior brain
- fruitless expressing neuron
- supraesophageal ganglion neuron
Relationships
- bearer of: unilateral
- capable_of_part_of: backward locomotion, flight behavior, jump response, neuromuscular process controlling posture
- fasciculates with: ventral median tract of ventral cervical fasciculus
- has soma location: adult posterior brain cell body rind, cell body rind of adult posterior lateral protocerebrum
- has synaptic IO in region: adult T2 leg neuropil, intermediate tectulum, lower tectulum
- is part of: adult central nervous system
- receives synaptic input from neuron: lobula columnar neuron LC4
- receives synaptic input in region: LC4 optic glomerulus, antennal mechanosensory and motor center zone A, antennal mechanosensory and motor center zone B, wedge
- sends synaptic output to region: adult gnathal ganglion, saddle
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| DNp02 | exact synonym | doi_10_7554_eLife_97766_1 |
| DNlt003 | exact synonym | Stürner et al., 2025 |
| DNp02 | exact synonym | Namiki et al., 2018 |
| DNp02 | exact synonym | Bates et al., 2025 |
| antennal mechanosensory and motor center AMMC P3b neuron | exact synonym | Stürner et al., 2025 |
| DNp02 | exact synonym | Berg et al., 2025 |
| DNp02 | exact synonym | |
| DNp02 | exact synonym | Scheffer et al., 2020 |
| DNp02 | exact synonym | Schlegel et al., 2024 |
| AMMC-P3b | exact synonym | Stürner et al., 2025 |
List all available images of DNp02 (13 total)
| Thumbnail | Name | Tags |
|---|---|---|
| DNp02_L (MaleCNS:10197) | Adult, Cholinergic, lineage_SMPpv2_CP1 | |
| DNp02_L (MaleCNS:10197) | Adult, Cholinergic, lineage_SMPpv2_CP1 | |
| DNp02_R (MaleCNS:10117) | Adult, Cholinergic, lineage_SMPpv2_CP1 | |
| DNp02_R (MaleCNS:10117) | Adult, Cholinergic, lineage_SMPpv2_CP1 | |
| TBD (MANC:10331) | Nervous_system, Adult, Cholinergic |
Expression patterns overlapping DNp02 (9 total)
| Thumbnail | Name | Tags |
|---|---|---|
| P{R24A03-GAL4.DBD} ∩ P{VT063736-p65.AD} expression pattern | Split | |
| P{R24A03-GAL4.DBD} ∩ P{R31B08-p65.AD} expression pattern | Split | |
| P{R24A03-GAL4.DBD} ∩ P{R29F12-p65.AD} expression pattern | Split | |
| P{R15E12-GAL4.DBD} ∩ P{VT025392-p65.AD} expression pattern | Split | |
| P{GawB}NP7365 expression pattern | Expression_pattern |
Transgene expression in DNp02 (9 total)
| Thumbnail | Name | Tags |
|---|---|---|
| P{R24A03-GAL4.DBD} ∩ P{VT063736-p65.AD} expression pattern | Split | |
| P{R24A03-GAL4.DBD} ∩ P{R31B08-p65.AD} expression pattern | Split | |
| P{R24A03-GAL4.DBD} ∩ P{R29F12-p65.AD} expression pattern | Split | |
| P{R15E12-GAL4.DBD} ∩ P{VT025392-p65.AD} expression pattern | Split | |
| P{GawB}NP7365 expression pattern | Expression_pattern |
Downstream connectivity classes for DNp02 (344 total)
| Thumbnail | Name | Tags |
|---|---|---|
Upstream connectivity classes for DNp02 (240 total)
| Thumbnail | Name | Tags |
|---|---|---|
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