DNp11 [FBbt_00047644]
DNp11
ID: FBbt_00047644
Descending neuron belonging to the DNp group, having a cell body posterior to the inferior posterior slope (Matsuo et al., 2016; Namiki et al., 2018). The primary neurite extends anterodorsally and branches in the posterior region of the posterior ventrolateral protocerebrum, with one branch extending laterally to form postsynaptic terminals in the lobula (Matsuo et al., 2016). A ventral branch forms a dense dendritic arbor encompassing the ipsilateral antennal mechanosensory and motor center zone B, wedge, posterior lateral protocerebrum, and anterior and posterior ventrolateral protocerebrum, including the LC4 glomerulus and non-glomerular regions (Matsuo et al., 2016). A thin neurite projects medially and fasciculates with the great commissure, then turns ventrally and forms presynaptic terminals bilaterally in the saddle and posterior gnathal ganglion (Matsuo et al., 2016). Some individuals may have additional ipsilateral brain innervation (Matsuo et al., 2016). It descends on the contralateral side of the cervical connective, fasciculates with the median tract of the dorsal cervical fascicle and innervates the intermediate and lower tectulum, abdominal neuromere, and T1 and T2 leg neuropils (Namiki et al., 2018). There is one of these cells per hemisphere (Matsuo et al., 2016; Namiki et al., 2018). It receives looming stimulus input from posterior LC4 neurons and its activity results in a forwards leaning posture and forwards takeoff (Dombrovski et al., 2023).
Db3a,b,c subtypes from Matsuo et al. (2016) represent individual differences in Db3 (DNp11) neurons, rather than distinct types.
Open in VFB 3D Browser →- adult visual projection neuron
- antennal mechanosensory and motor center B projection neuron
- descending neuron of the posterior brain
- great commissural interneuron
- wedge projection neuron
Relationships
- bearer of: bilateral
- capable_of_part_of: flight behavior, jump response, locomotion, neuromuscular process controlling posture
- fasciculates with: adult median tract of dorsal cervical fasciculus
- has soma location: adult posterior brain cell body rind
- has synaptic IO in region: adult T1 leg neuropil, adult T2 leg neuropil, adult abdominal neuromere, intermediate tectulum, lower tectulum
- receives synaptic input from neuron: lobula columnar neuron LC4
- receives synaptic input in region: LC4 optic glomerulus, anterior ventrolateral protocerebrum, lobula, posterior lateral protocerebrum
- sends synaptic output to region: adult gnathal ganglion, saddle
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| antennal mechanosensory and motor center AMMC Db3c neuron | narrow synonym | Matsuo et al., 2016 |
| antennal mechanosensory and motor center AMMC Db3a neuron | narrow synonym | Matsuo et al., 2016 |
| AMMC-Db3b | narrow synonym | Matsuo et al., 2016 |
| antennal mechanosensory and motor center AMMC Db3b neuron | narrow synonym | Matsuo et al., 2016 |
| AMMC-Db3c | narrow synonym | Matsuo et al., 2016 |
| AMMC-Db3a | narrow synonym | Matsuo et al., 2016 |
| antennal mechanosensory and motor center AMMC Db3 neuron | exact synonym | Matsuo et al., 2016 |
| DNp11 | exact synonym | doi_10_7554_eLife_97766_1 |
| AMMC-Db3 | exact synonym | Matsuo et al., 2016 |
| DNp11 | exact synonym | Bates et al., 2025 |
| DNp11 | exact synonym | Berg et al., 2025 |
| DNp11 | exact synonym | Namiki et al., 2018 |
| DNxn029 | exact synonym | Stürner et al., 2025 |
| DNp11 | exact synonym | Scheffer et al., 2020 |
| DNp11 | exact synonym | |
| DNp11 | exact synonym | Schlegel et al., 2024 |
| DNp11 | exact synonym | Nern et al., 2025 |
List all available images of DNp11 (17 total)
| Thumbnail | Name | Tags |
|---|---|---|
| DNp11_L (MaleCNS:10259) | Nervous_system, Adult, Visual_system, Cholinergic | |
| DNp11_R (MaleCNS:10106) | Nervous_system, Adult, Visual_system, Cholinergic | |
| DNp11_R (MaleCNS:10106) | Nervous_system, Adult, Visual_system, Cholinergic | |
| TBD (MANC:10122) | Nervous_system, Adult, Visual_system, Cholinergic | |
| TBD (MANC:10122) | Nervous_system, Adult, Visual_system, Cholinergic |
Expression patterns overlapping DNp11 (6 total)
| Thumbnail | Name | Tags |
|---|---|---|
| P{VT017928-GAL4.DBD} ∩ P{VT004985-p65.AD} expression pattern | Split | |
| P{VT017682-GAL4.DBD} ∩ P{VT048835-p65.AD} expression pattern | Split | |
| P{R15E12-GAL4.DBD} ∩ P{VT025392-p65.AD} expression pattern | Split | |
| P{GMR44D02-GAL4} expression pattern | Expression_pattern | |
| P{GawB}NP7365 expression pattern | Expression_pattern |
Transgene expression in DNp11 (6 total)
| Thumbnail | Name | Tags |
|---|---|---|
| P{VT017928-GAL4.DBD} ∩ P{VT004985-p65.AD} expression pattern | Split | |
| P{VT017682-GAL4.DBD} ∩ P{VT048835-p65.AD} expression pattern | Split | |
| P{R15E12-GAL4.DBD} ∩ P{VT025392-p65.AD} expression pattern | Split | |
| P{GMR44D02-GAL4} expression pattern | Expression_pattern | |
| P{GawB}NP7365 expression pattern | Expression_pattern |
Downstream connectivity classes for DNp11 (551 total)
| Thumbnail | Name | Tags |
|---|---|---|
Upstream connectivity classes for DNp11 (371 total)
| Thumbnail | Name | Tags |
|---|---|---|
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