DNp11 [FBbt_00047644]

Descending neuron belonging to the DNp group, having a cell body posterior to the inferior posterior slope (Matsuo et al., 2016; Namiki et al., 2018). The primary neurite extends anterodorsally and branches in the posterior region of the posterior ventrolateral protocerebrum, with one branch extending laterally to form postsynaptic terminals in the lobula (Matsuo et al., 2016). A ventral branch forms a dense dendritic arbor encompassing the ipsilateral antennal mechanosensory and motor center zone B, wedge, posterior lateral protocerebrum, and anterior and posterior ventrolateral protocerebrum, including the LC4 glomerulus and non-glomerular regions (Matsuo et al., 2016). A thin neurite projects medially and fasciculates with the great commissure, then turns ventrally and forms presynaptic terminals bilaterally in the saddle and posterior gnathal ganglion (Matsuo et al., 2016). Some individuals may have additional ipsilateral brain innervation (Matsuo et al., 2016). It descends on the contralateral side of the cervical connective, fasciculates with the median tract of the dorsal cervical fascicle and innervates the intermediate and lower tectulum, abdominal neuromere, and T1 and T2 leg neuropils (Namiki et al., 2018). There is one of these cells per hemisphere (Matsuo et al., 2016; Namiki et al., 2018). It receives looming stimulus input from posterior LC4 neurons and its activity results in a forwards leaning posture and forwards takeoff (Dombrovski et al., 2023).
DNp11 DNp11 DNp11 DNp11

DNp11

ID: FBbt_00047644

Adult Nervous system Neuron Visual system

Descending neuron belonging to the DNp group, having a cell body posterior to the inferior posterior slope (Matsuo et al., 2016; Namiki et al., 2018). The primary neurite extends anterodorsally and branches in the posterior region of the posterior ventrolateral protocerebrum, with one branch extending laterally to form postsynaptic terminals in the lobula (Matsuo et al., 2016). A ventral branch forms a dense dendritic arbor encompassing the ipsilateral antennal mechanosensory and motor center zone B, wedge, posterior lateral protocerebrum, and anterior and posterior ventrolateral protocerebrum, including the LC4 glomerulus and non-glomerular regions (Matsuo et al., 2016). A thin neurite projects medially and fasciculates with the great commissure, then turns ventrally and forms presynaptic terminals bilaterally in the saddle and posterior gnathal ganglion (Matsuo et al., 2016). Some individuals may have additional ipsilateral brain innervation (Matsuo et al., 2016). It descends on the contralateral side of the cervical connective, fasciculates with the median tract of the dorsal cervical fascicle and innervates the intermediate and lower tectulum, abdominal neuromere, and T1 and T2 leg neuropils (Namiki et al., 2018). There is one of these cells per hemisphere (Matsuo et al., 2016; Namiki et al., 2018). It receives looming stimulus input from posterior LC4 neurons and its activity results in a forwards leaning posture and forwards takeoff (Dombrovski et al., 2023).

Db3a,b,c subtypes from Matsuo et al. (2016) represent individual differences in Db3 (DNp11) neurons, rather than distinct types.

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
antennal mechanosensory and motor center AMMC Db3c neuron narrow synonym Matsuo et al., 2016
antennal mechanosensory and motor center AMMC Db3a neuron narrow synonym Matsuo et al., 2016
AMMC-Db3b narrow synonym Matsuo et al., 2016
antennal mechanosensory and motor center AMMC Db3b neuron narrow synonym Matsuo et al., 2016
AMMC-Db3c narrow synonym Matsuo et al., 2016
AMMC-Db3a narrow synonym Matsuo et al., 2016
antennal mechanosensory and motor center AMMC Db3 neuron exact synonym Matsuo et al., 2016
DNp11 exact synonym doi_10_7554_eLife_97766_1
AMMC-Db3 exact synonym Matsuo et al., 2016
DNp11 exact synonym Bates et al., 2025
DNp11 exact synonym Berg et al., 2025
DNp11 exact synonym Namiki et al., 2018
DNxn029 exact synonym Stürner et al., 2025
DNp11 exact synonym Scheffer et al., 2020
DNp11 exact synonym
DNp11 exact synonym Schlegel et al., 2024
DNp11 exact synonym Nern et al., 2025

List all available images of DNp11 (17 total)

Thumbnail Name Tags
DNp11_L (MaleCNS:10259) Nervous_system, Adult, Visual_system, Cholinergic
DNp11_R (MaleCNS:10106) Nervous_system, Adult, Visual_system, Cholinergic
DNp11_R (MaleCNS:10106) Nervous_system, Adult, Visual_system, Cholinergic
TBD (MANC:10122) Nervous_system, Adult, Visual_system, Cholinergic
TBD (MANC:10122) Nervous_system, Adult, Visual_system, Cholinergic

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Expression patterns overlapping DNp11 (6 total)

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Transgene expression in DNp11 (6 total)

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Downstream connectivity classes for DNp11 (551 total)

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Upstream connectivity classes for DNp11 (371 total)

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