l-LNv [FBbt_00003763]

Neuron of the period-expressing LNv cluster of the adult brain, with a large cell body and generally located more dorsally than the s-LNv neurons (Helfrich-Forster, 1998). There are four of these cells per hemisphere, all of which express Pdf (Helfrich-Forster et al., 2007). These neurons send dendrites through the posterior optic commissure to the contralateral optic lobe, where a few short fibers terminate in the accessory medulla, but most arborize extensively in the medulla itself (Helfrich-Forster, 2005; Helfrich-Forster et al., 2007). These arborizations in the medulla are associated with varicosities. These cells also project to the ipsilateral (adjacent) accessory medulla and its ventral extension, where they arborize extensively.
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l-LNv l-LNv l-LNv l-LNv

l-LNv

ID: FBbt_00003763

Adult Nervous system Peptidergic Sensory neuron Visual system

Neuron of the period-expressing LNv cluster of the adult brain, with a large cell body and generally located more dorsally than the s-LNv neurons (Helfrich-Forster, 1998). There are four of these cells per hemisphere, all of which express Pdf (Helfrich-Forster et al., 2007). These neurons send dendrites through the posterior optic commissure to the contralateral optic lobe, where a few short fibers terminate in the accessory medulla, but most arborize extensively in the medulla itself (Helfrich-Forster, 2005; Helfrich-Forster et al., 2007). These arborizations in the medulla are associated with varicosities. These cells also project to the ipsilateral (adjacent) accessory medulla and its ventral extension, where they arborize extensively.

While l-LNv neurons fit the definition of pacemaker neurons based on molecular oscillation of Period (FBgn0003068) and Timeless (FBgn0014396) expression, they do not sustain this molecular oscillation when kept in constant darkness (Yang and Sehgal, 2001; Shafer et al., 2002). Synaptobrevin localization supports the assertion that projections through the posterior optic commissure to the contralateral optic lobe are dendritic (Helfrich-Forster et al., 2007).

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
lLNv exact synonym
large pigment-dispersing hormone-immunoreactive neuron close to medulla exact synonym
large LNv exact synonym
l-LNv exact synonym Scheffer et al., 2020
l-LNv exact synonym Nern et al., 2025
l-LNv exact synonym Schlegel et al., 2024
l-LNv exact synonym
l-vLN exact synonym Shafer and Taghert, 2009