MeLo3a [FBbt_00053502]

Adult unilateral optic-lobe-intrinsic neuron with its soma on the ventral side of the lobula (Dorkenwald et al., 2024; Schlegel et al., 2024; Nern et al., 2025). It bifurcates near the soma, sending one branch to the medulla and one to the lobula, without passing through the optic chiasm (Nern et al., 2025). It receives input, but also has presynapses, primarily in medulla layers M3-M4 in around 10-15 columns, with a smaller amount of input in M6-M8 (Nern et al., 2025). It also has pre- and post-synapses in the lobula, in a few columns of layers 5B-6 (Nern et al., 2025). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024; Nern et al., 2025). There are approximately 50 of these cells per hemisphere (Nern et al., 2025).
MeLo3a MeLo3a MeLo3a MeLo3a

MeLo3a

ID: FBbt_00053502

Adult Cholinergic Nervous system Visual system

Adult unilateral optic-lobe-intrinsic neuron with its soma on the ventral side of the lobula (Dorkenwald et al., 2024; Schlegel et al., 2024; Nern et al., 2025). It bifurcates near the soma, sending one branch to the medulla and one to the lobula, without passing through the optic chiasm (Nern et al., 2025). It receives input, but also has presynapses, primarily in medulla layers M3-M4 in around 10-15 columns, with a smaller amount of input in M6-M8 (Nern et al., 2025). It also has pre- and post-synapses in the lobula, in a few columns of layers 5B-6 (Nern et al., 2025). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024; Nern et al., 2025). There are approximately 50 of these cells per hemisphere (Nern et al., 2025).

Cell type identified in two sets of EM data (Matsliah et al., 2024; Nern et al., 2024).

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
MLt2 exact synonym Nern et al., 2025
MeLo3a exact synonym Berg et al., 2025
MLt2 exact synonym Schlegel et al., 2024
MeLo3a exact synonym Nern et al., 2025
MeLo3a exact synonym

List all available images of MeLo3a (275 total)

Thumbnail Name Tags
MeLo3a_L (MaleCNS:548185) Nervous_system, Adult, Visual_system, Cholinergic
MeLo3a_L (MaleCNS:91678) Nervous_system, Visual_system, Adult, Cholinergic
MeLo3a_R (MaleCNS:43259) Nervous_system, Visual_system, Adult, Cholinergic
MeLo3a_R (MaleCNS:70850) Nervous_system, Adult, Visual_system, Cholinergic
MeLo3a_R (MaleCNS:73985) Nervous_system, Visual_system, Adult, Cholinergic

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Downstream connectivity classes for MeLo3a (289 total)

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Upstream connectivity classes for MeLo3a (255 total)

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